Skip to main content

Campus San Felipe

Dra. Alejandra Espinosa Escalona

Profesor Titular, Escuela de medicina
Asignaturas:
  • Estructura y función celular.
  • Organismo humano II.
  • Metodología de la Investigación.
  • Fisiopatología.
Información académica:
  • Tecnólogo Médico con mención en Laboratorio clínico, Hematología y Banco de Sangre
  • Magíster en Ciencias Biológicas con mención en Bioquímica y Biología Molecular
  • Doctor en Ciencias Biomédicas
Proyectos de investigación:
  • Multidisciplinary study of technological processing to improve the functional and healthy properties of wine and beer bagasse of Valparaíso region” Proyecto R23F0004. Concurso: Fortalecimiento al Desarrollo Científico-Tecnológico de Centros Regionales 2023. Duración 4 años (fecha de inicio 13/12/23). Dra. Alejandra Espinosa (Investigador Principal).
Publicaciones (últimos 5 años):
  • Beyer MP, Mercado-Lopez L, Farias C, Carrasco-Gutiérrez R, Espinosa A, Dagnino-Subiabre A, et al. Impact of perinatal α-linolenic acid deficiency combined with high-fat diet consumption on tissue-specific fatty acid profiles in rats: Maternal and offspring analysis. Prostaglandins Leukot Essent Fatty Acids. 2026;208:102723.
  • Bucarey JL, Casas M, Espinosa A. Mitochondrial Iron Handling and Lipid Peroxidation as Drivers of Ferroptosis. Int J Mol Sci. 2026;27(5):2232.
  • Soto-Maldonado C, Espinosa A, Bucarey JL, Fuentes L. Functional Benefits of Brewer’s Spent Grain and the Challenge of Developing Food Ingredients for Human Health. Antioxidants. 2026;15(2):247.
  • Claria B, Espinosa A, Rodríguez A, et al. Effect of Supplementation of Antioxidant Lipids Synthetized by Enzymatic Acidolysis with EPA/DHA Concentrate and Maqui (Aristotelia chilensis) Seed Oil for Mitigating High-Fat Diet-Induced Obesity and Metabolic Disorders in Mice. Antioxidants. 2025.
  • Lorena Mercado-López, Yasna Muñoz, Camila Farias, María Paz Beyer, Robinson Carrasco-Gutiérrez, Angie Vanessa Caicedo-Paz, Alexies Dagnino-Subiabre, Alejandra Espinosa and Rodrigo Valenzuela. High-Fat Diet in Perinatal Period Promotes Liver Steatosis and Low Desaturation Capacity of Polyunsaturated Fatty Acids in Dams: A Link with Anxiety-Like Behavior in Rats. Nutrients. 2025.
  • Zúñiga-Hernández J, Farias C, Espinosa A, et al. Modulation of Δ5- and Δ6-desaturases in the brain-liver axis. Nutrition. 2025.
  • Luis P, Diego N, Alejandra E. Physalis peruviana intake against noncommunicable chronic diseases: a biomedical approach. In: Handbook of Goldenberry (Physalis peruviana). Elsevier; 2024. p. 255–270.
  • Bórquez JC, Díaz-Castro F, La Fuente FP, Espinoza K, Figueroa AM, Martínez-Ruíz I, et al. Mitofusin-2 induced by exercise modifies lipid droplet-mitochondria communication, promoting fatty acid oxidation in male mice with NAFLD. Metabolism. 2023.
  • Álvarez D, Ortiz M, Valdebenito G, Crisosto N, Echiburú B, Valenzuela R, et al. Effects of a High-Fat Diet and Docosahexaenoic Acid during Pregnancy on Fatty Acid Composition in the Fetal Livers of Mice. Nutrients. 2023;15(21):4696.
  • Espinosa A, Casas M, Jaimovich E. Energy (and Reactive Oxygen Species Generation) Saving Distribution of Mitochondria for the Activation of ATP Production in Skeletal Muscle. Antioxidants. 2023;12(8):1624.
  • Maturana G, Segovia J, Olea-Azar C, Uribe-Oporto E, Espinosa A, Zúñiga-López MC. Evaluation of the Effects of Chia (Salvia hispanica L.) Leaves Ethanolic Extracts Supplementation. Antioxidants. 2023;12(5):1108.
  • Apablaza P, Bórquez JC, Mendoza R, Silva M, Tapia G, Espinosa A, et al. Exercise Induces an Augmented Skeletal Muscle Mitochondrial Unfolded Protein Response. Int J Mol Sci. 2023;24(6):5654.
  • Vásquez-Trincado C, Navarro-Márquez M, Morales PE, Westermeier F, Chiong M, Parra V, et al. Myristate induces mitochondrial fragmentation. Front Cell Dev Biol. 2023;11:1072315.
  • Jannas-Vela S, Espinosa A, Candia AA, Flores-Opazo M, Peñailillo L, Valenzuela R. Role of Omega-3 Fatty Acids in Skeletal Muscle Regeneration. Nutrients. 2023;15(4):871.
  • Dovale-Rosabal G, Espinosa A, Rodríguez A, Barriga A, Palomino-Calderón A, Romero N, et al. Structured Phenolic Lipids against MAFLD. Molecules. 2022;27(22):7702.
  • Espinosa A, Morrison R, Gonzalez D, Jamardo J, Fortuna F, Díaz CP, et al. Active Meditation and Hair Cortisol Levels. Occup Ther Int. 2022;2022:2174397.
  • Pino-de la Fuente F, Bórquez JC, Díaz-Castro F, Espinosa A, Chiong M, Troncoso R. Exercise regulation of hepatic lipid metabolism. Life Sci. 2022;298:120522.
  • Barrera C, Valenzuela R, Rincón MA, Espinosa A, López-Arana S, González-Mañan D, et al. Prostaglandins Leukot Essent Fatty Acids. 2020;153:102058
  • Fuente FP de la, Nocetti D, Sacristán C, Ruiz P, Guerrero J, Jorquera G, et al. Nutrients. 2020;12(3):700.
  • Illesca P, Valenzuela R, Espinosa A, Echeverría F, Soto-Alarcon S, Campos C, et al. Molecules. 2020;25(19):4433.
  • Ortiz M, Soto-Alarcón SA, Orellana P, Espinosa A, Campos C, López-Arana S, et al. Dig Liver Dis. 2020;52(8):895–904.
  • Dassonvalle J, Díaz-Castro F, Donoso-Barraza C, Sepúlveda C, Pino-de la Fuente F, Pino P, et al. Int J Mol Sci. 2020;21(20):7582.
  •  Illesca P, Valenzuela R, Espinosa A, Echeverría F, Soto-Alarcón S, Ortiz M, et al. Food Funct. 2020;11(10):9086–102.